White Sox vs. Twins odds, prediction, line, time: 2023 MLB picks, Monday, April 10 best bets from proven model

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White Sox vs. Twins odds, prediction, line, time: 2023 MLB picks, Monday, April 10 best bets from proven model

The Minnesota Twins will look to continue their solid start to the season when they battle the Chicago White Sox in an early-season American League Central matchup on Monday. The Twins (6-3), who have won two of their first three series of the season, are 2-1 in their last three games and lead the division by one game over the Cleveland Guardians. The White Sox (4-6), who split their opening series with Houston, have dropped the past two series since. Minnesota has won eight of the past 13 home games against Chicago.

The game is slated to begin at 2:10 p.m. ET from Target Field in Minneapolis. The White Sox have the third-best team batting average at .287, while the Twins are batting .240, 21st-best. Chicago is a -125 favorite on the money line (risk $125 to win $100) in the latest White Sox vs. Twins odds from Caesars Sportsbook, while the over/under for total runs scored is 7.5. Before making any Twins vs. White Sox picks, be sure to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons, and it finished the 2022 MLB season on a 20-14 roll. Anybody who has followed it has seen profitable returns.

Now, the model has dialed in on White Sox vs. Twins and revealed its predictions and best bets. You can visit SportsLine now to see the model's MLB picks. Here are the MLB odds and betting trends for Twins vs. White Sox:

  • White Sox vs. Twins money line: Chicago -125, Minnesota +105
  • White Sox vs. Twins over/under: 7.5 runs
  • White Sox vs. Twins run line: Minnesota -1.5 (+196)
  • CWS: The Over is 5-0 in the White Sox's last five road games
  • MIN: The Twins are 4-0 in their last four games against the American League Central
  • White Sox vs. Twins picks: See picks at SportsLine

Featured Game| Minnesota Twins vs. Chicago White Sox

Why you should back the Twins

Center fielder Byron Buxton enters the series with a four-game hitting streak. In Friday's 3-2 win over the Houston Astros, Buxton was 2-for-5. He has had four multi-hit games on the season. He is batting .324 with one homer, three RBI and seven runs scored. Buxton has feasted on White Sox pitching throughout his career. In 66 games, he is hitting .280 with 20 doubles, one triple, 15 homers and 37 RBI. He also has seven stolen bases in eight attempts.

Shortstop Kyle Farmer is also off to a hot start to the year. He is hitting .318 with one homer, five RBI and six runs scored. In Saturday's 9-6 win over the Astros, Farmer was 3-for-4 with a double, home run and three RBI. He is a career .348 hitter at Target Field with a homer and five RBI. Starting pitcher Kenta Maeda took the loss, but gave up just three hits, one run and struck out nine in his debut this season.

Why you should back the White Sox

Chicago is expected to send right-hander Dylan Cease (1-0, 1.59 ERA) to the hill. In two starts this season, he has allowed just three hits in 11.1 innings. He has walked five, while striking out 18. In a 7-3 win over San Francisco on Wednesday, he picked up the victory, going five innings, while allowing just one hit -- a solo home run by J.D. Davis -- while walking five and striking out eight. In nine career starts against the Twins, he is 3-4 with a 5.14 ERA, pitching 49 innings and allowing 45 hits, 28 earned runs and 22 walks, while striking out 53.

Center fielder Luis Robert Jr. has been red hot, with five multi-hit games so far. In two games against the Pittsburgh Pirates this past weekend, he was 5-for-10 with a double, two homers and seven RBI with two runs scored. For the season, he is hitting .366 with four homers, 10 RBI and seven runs scored. In 17 career games against Minnesota, he is batting .267 with four doubles, four homers and 14 RBI.

How to make Twins vs. White Sox picks

SportsLine's model is leaning Over on the run total, as the simulations have the teams combining for 8.6 runs. It also says one side of the money line has all the value. You can only get the model's pick at SportsLine.