Trevor Lawrence NFL Player Props, Odds Week 10: Predictions for 49ers vs. Jaguars

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Trevor Lawrence NFL Player Props, Odds Week 10: Predictions for 49ers vs. Jaguars

Our Trevor Lawrence NFL player prop predictions based on the best NFL odds question whether the Jacksonville Jaguars signal-caller could run into a motivated San Francisco 49ers defense in Week 10.

The Jacksonville Jaguars are riding high to this point of the season, boasting one of the best records in the AFC.

The recent struggles of the San Francisco 49ers might indicate potential challenges, making it seem like the Jacksonville Jaguars could have another strong outing at home this week. However, a notable addition to the Niners' defensive line at the trade deadline brings a significant boost that could help the team regain momentum and get back on track. Despite the 49ers' recent difficulties, the trade deadline acquisition suggests a strategic effort to strengthen their defensive capabilities, potentially altering the dynamics and performance of the team as they aim to overcome challenges and secure a positive outcome in the upcoming game.

NFL Week 10 predictions and 49ers-Jaguars prop predictions, along with our Week 10 NFL props to accompany our best Trevor Lawrence NFL player prop predictions (odds via our best NFL betting sites; Pick confidence is based on a 1-to-5-star scale).

Trevor Lawrence NFL player prop predictions for Week 10

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Trevor Lawrence player props

Trevor Lawrence Over 23.5 completions (+100 via DraftKings) ⭐⭐⭐⭐

Trevor Lawrence has led the Jaguars to five straight wins entering Week 10, but it’s not entirely accurate to say that he’s carried the team all by himself during this stretch. During the streak, the Jacksonville defense has held opponents to 16.2 points per game.

But this week against San Francisco, we could see Lawrence asked to shoulder more of the offensive responsibilities. The Niners have a team total of 24.5 points, meaning it could take more from Lawrence to compete in this one. That’s especially true if San Francisco’s fifth-ranked rushing defense (86.1 opponent rushing yards per game) limits Jags running back Travis Etienne.

Because of their run-stuffing nature, the Niners tend to allow opposing quarterbacks to complete more passes than most teams--because teams are throwing more against them. Lawrence has cleared this 23.5-completion line four times, but I like his chances against a team allowing 26.5 completions per game (30th in the NFL). At +100 odds, DraftKings has the best odds on this prop.

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Trevor Lawrence Over 15.5 rushing yards (-110 via bet365) ⭐⭐⭐

Quarterbacks with solid mobility like Cincinnati Bengals quarterback Joe Burrow and then Arizona Cardinals signal-caller Joshua Dobbs have found success exploiting that element of the run defense against San Francisco to the extent that it’s worth scoping out the lines on Lawrence’s rushing yards.

Seeing the prop line at 15.5 yards makes it a solid play. Lawrence has cleared this mark five times, landing right below it at 15 yards on the dot in one other game. His efficiency when he takes off to run has been strong, as Lawrence has averaged 5.1 yards per carry this season. He’s had at least one carry of 8+ yards in every game played; as long as he scampers at least a few times, precedent suggests he gets there.

Avoid FanDuel for a bet on this prop (16.5 yards, -114). Our other best sports betting apps offer the line at 15.5, but spots like Caesars (-117) and DraftKings (-125) don’t offer compelling odds on Over. Head to bet365 for -110 odds on the 15.5-yard line.

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Lawrence Under 1.5 passing touchdowns (-135 via bet365) ⭐⭐⭐

Jacksonville’s team total sits at 20.5 for this game, so a couple of touchdowns should be in the cards. And the 49ers aren’t impenetrable against the pass, allowing 1.3 passing TDs per game on the year.

At the end of the day, we like Lawrence to post solid passing numbers. But it’s difficult to project multiple passing touchdowns for the Jaguars in this matchup against a San Francisco defense debuting newly acquired Chase Young on the pass rush. Though San Francisco is stingy against the run, Jacksonville wants to run it in the red zone; Etienne has three multi-touchdown games in the past four weeks, which could boost our cause here if he eats up some of Lawrence’s scoring chances.

Stay away from FanDuel’s inflated -160 odds on this Under bet. DraftKings and BetMGM offer acceptable value at -140, and the same story for Caesars at -137. But bet365 comes in again with the best odds on this one at -135.

Trevor Lawrence player prop picks made 11/11/2023 at 10:50 a.m. ET.

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