Air Force vs. Wyoming odds, prediction, spread: 2022 Week 3 college football picks from model on 50-41 run

Air Force Falcons are looking to start the season 3-0 for the first time since 2016. They take on the Wyoming Cowboys in a Mountain West Conference Mountain Division opener on Friday. The game can be seen on CBS Sports Network. Air Force led the nation in rushing offense in 2021, averaging 328.2 yards per game. Wyoming averaged 211.7 rushing yards. This is the 60th meeting between the teams.

Air Force is 6-0 against the spread in their last six games and Wyoming is 8-1 ATS in its last nine home games against a team with a winning road record. Wyoming and Air Force are playing each other in college football on Saturday.

Air Force is 6-0 against the spread in their last six games. Wyoming is 8-1 ATS in its last nine home games against a team with a winning road record.

Air Force leads the nation in rushing with a 508.5 average. The Falcons rushed for 582 yards in the season opener vs. Northern Iowa. Senior running back Brad Roberts has carried 32 times for 288 yards and four touchdowns. Haaziq Daniels is a dual threat quarterback who has completed 4 of 11 passes for 117 yards (10.6 average) and one touchdown. He has also rushed 21 times, with 6. 5 average, and has two touchdowns, which is the only FBS player to hold school records for both longest run and pass.

Andrew Peasley was named the Mountain West Conference Offensive Player of the Week for his performance in leading Wyoming to a 40-37 double-overtime home win over Tulsa two weeks ago. Last week against Northern Colorado, Peasell completed 19 of 30 passes (63.3%) for 144 yards in a 33-10 victory. John Hoyland was the Special Teams Player for the conference two week ago and he was 4-for-4 on field goals and 3- for-3 on extra points.

Air Force is favored by 50 points against Wyoming. SportsLine's model is leaning Over on the total. It has also generated an against-the-spread pick that cashes in almost 60% of simulations.