College Football Betting Trends to Know for Week 4: Can Fighting Irish Remain Road Warriors?

This Saturday's college football betting slate offers an eclectic mix of both conference and non-league games. Notre Dame's offense is going to have a breakout on the road at North Carolina. Tennessee is at home against Florida. The trends specific to the Week 4 matchups can help jump-start a more thorough handicap.

Notre Dame's offense ranks 105th in the country this season. The Fighting Irish have averaged only 18.3 points per game. Notre Dame is 18-8 against the spread on the road when facing teams averaging 36 points or more. North Carolina is a slight favorite ahead of Saturday's game in Chapel Hill. The Tar Heels are on a 3-0 run both straight up and as a bettter.

Road teams are a perfect 5-0 ATS in the last five meetings between South Florida and Louisville. The Cardinals are 14.5 points behind the Bulls. Louisville has won three straight games in this series. USF won last week on the road against Florida. Louisville's defense is ranked 98th in FBS in terms of rushing defense. South Fours teams have combined for 3 rushing touchdowns in 3 games.

Tennessee is a 10.5-point favorite over Florida in Saturday's college football game. The game could determine which team finishes second to Georgia in the SEC East Division in 2022.

The Gators have won 16 of the last 17 meetings between the schools dating back to 2005. The Vols are a heavy underdog, but they won the game in Knoxville last time. Florida hasn't looked impressive since upsetting Utah in Week 1. Quarterback Anthony Richardson has yet to throw a touchdown pass.

Wisconsin is 8-2 in the last 10 road games against teams ranked in AP Top-10. The Badgers haven't played against an AP top-ten team since a 28-7 loss at Iowa in 2020. Ohio State is a 19-point favorite for Saturday's game against Wisconsin.

Wisconsin lost to Washington State two weeks ago. The Badgers' offense has struggled to move the ball. They face an experienced and improved Buckeyes defense.

Wyoming is on a three-plus game winning streak. The Cowboys are 3-1 and play at home against BYU on Saturday. Wyoming's defense is improving. BYU's offense is more versatile and the team's running back is still finding his stride. The team is under the odds. It has hit 11 times over the last 15 times when on the three or more game win streak and is 11-4 in the games when it's under 50 points.

College Football Betting Trends to Know for Week 4: Can Fighting Irish Remain Road Warriors? picks, odds, and sports betting news.