College Football Week 4 Odds, Best Bets & Picks

Georgia, Alabama and Ohio State are the consensus top three on the college football playoff odds board. USC, Clemson, Michigan and Florida are in the top six. The rest of the field is priced at 40-1 or longer on betting apps. Clemson (-7.5) faces a tough road test at Wake Forest, Ohio is hosting the Badgers and No. 20 Florida takes on No 11 Tennessee.

College Football Week 4 odds are available at sportsbooks and on available betting apps. The best bets and picks for the CFB Week Four are also available.

College Football Week 4 Odds, Best Bets & Picks. Florida vs. Tennessee and Wisconsin vs Ohio State are the best bets.

Maryland is 3-0 and coming off a gritty win over SMU. Michigan hasn't been tested at all in three home wins over Colorado State, Hawaii and UConn. The Terps figure to test the Wolverines through the air early and often. Michigan should pull away in the second half and cover.

Clemson and Wake Forest are playing each other on September 24 at noon ET. Clemson has won the last 13 games against Wake. The game could have implications for the ACC title and College Football Playoff implications.

Baylor is a slight favorite over Iowa State. Iowa is 3-0 and won at rival Iowa 10-7. Baylor lost at BYU. The Bears gained valuable experience in the double-overtime loss at the BYU and should be ready to start conference play with a big road win.

Duke and Kansas are both unbeaten. They play each other on September 24 at noon ET. Kansas is favored by less than 10 points. The Jayhawks are second in the nation in rushing yards per attempt. Jalon Daniels is a dual-threat quarterback who can take over the game if necessary.

Florida is looking to avoid their first 0-2 start in SEC play since 1986. The Gators defense is legit, especially in the secondary. Tennessee has destroyed two MAC teams but managed just 27 points in regulation against Pitt.

Minnesota plays Michigan State on September 24 at 3:30 p.m. ET. The Gophers haven't won in East Lansing since 2006. Michigan's defense is in disarray after it was destroyed by Washington last weekend.

Arkansas and Texas A&M are playing each other on September 24 at 7 p.m. ET. The Aggies bounced back from the Appalachian State upset with an impressive home win over Miami. Arkansas is the No. 10-ranked team and is favored by 10 points.

Wisconsin and Ohio State are playing each other in the Big Ten. The Badgers are three-score underdogs. Ohio has won eight straight games over Wisconsin. Wisconsin won the last game 34-21 in Big 10 title game. The Buckeyes beat Notre Dame 21-10 in their season-opening game, but they have since lost to Arkansas State and Toledo.