College Football Odds: Iowa vs. Ohio State prediction, odds, pick

Iowa is a team that is strong on one side of the ball and incompetent on the other. The quarterback position is the problem. Iowa did not use the transfer portal this year. Ohio State has an elite offense and a good defense. Michigan is only team with a chance to beat Ohio in Big Ten Conference play this season. The Buckeyes have a large margin for error in 2022. They have an excellent offense with C.J. Stroud throwing the football to a fleet of skilled wide receivers. Their defense is not amazing, but it can get several stops per game and minimize damage.

Iowa has the best defense this season. The Hawkeyes can cover the 29.5-point spread against Ohio State if they hold the Buckeyes to under 30 points.

Iowa's defense is very strong, but the Hawkeyes haven't seen the speed of Ohio State's receivers. Ohio should be able to score 38 points in this game.

Iowa's defense will not do anything. Ohio State will probably score no more than 42 points. The under is the best play on this game.

Iowa and Ohio State are playing each other. The final score is under 49.5.