Colorado vs. Oregon odds, spread, time: 2023 college football picks, Deion Sanders predictions by proven model
The Colorado Buffaloes' Deion Sanders-led turnaround faces a major challenge on Saturday when the No. 19 Buffaloes hit the road to face the No. 10 Oregon Ducks at Autzen Stadium in Eugene, Ore. One year after the team went 1-11 and fired coach Karl Dorrell, Sanders and the Buffaloes (3-0) have become the biggest story in all of college football. They've already beaten TCU, Nebraska and Colorado State. Meanwhile the Ducks (3-0) are off to a 3-0 start for the fifth time since 2017. The game will be the Pac-12 opener for both teams.
Kickoff is scheduled for 3:30 p.m. ET. The Ducks are 21-point favorites in the latest Oregon vs. Colorado odds, while the over/under for total points scored is 70.5. Before you make any Colorado vs. Oregon picks, you need to see the college football predictions and betting advice from SportsLine's proven computer model.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed the model has seen huge returns.
Now, the model has set its sights on Oregon vs. Colorado and just revealed its picks and predictions. You can visit SportsLine now to see the model's CFB picks. Here are several college football odds and trends for Colorado vs. Oregon:
- Colorado vs. Oregon spread: Ducks -21
- Colorado vs. Oregon over/under: 70 points
- Colorado vs. Oregon money line: Ducks -1032, Buffaloes +635
- ORE: The Ducks rank second in the country in scoring offense (58.0 points per game)
- COL: Shedeur Sanders is second in the nation in total offense (397.3 yards per game)
- Colorado vs. Oregon live stream: fubo (try for free)
Why Oregon can cover
Oregon has an experienced and prolific quarterback in Bo Nix. A fifth-year senior who's in his second season in Eugene, Nix leads all active FBS quarterbacks with 50 career starts and ranks second in total offense (13,176 yards). This season he ranks 12th in the country in passing yards per game (297.7).
In addition, the Ducks have dominated the series against Colorado recently. Oregon has won three in a row in the series and nine of the last 10 and lead the all-time series 15-9. Last season Oregon blew out the Buffaloes, 49-10, in Boulder. See which team to pick here.
Why Colorado can cover
Quarterback Shedeur Sanders has been lights-out to start the season. One of the sons of coach Deion Sanders, the younger Sanders leads the country in completions per game (35.7) and ranks second in total offense (397.3 yards per game) and passing yards per game (417.0). Last week he made several clutch throws late in regulation and in overtime to rally Colorado to a 43-35 win over Colorado State.
In addition, the Buffaloes have done an excellent job of winning the turnover battle this season. Colorado has intercepted six passes this year, which is third in the country, and forced 10 turnovers total. Their +2.00 turnover margin per game ranks fourth in the nation. See which team to pick here.
How to make Oregon vs. Colorado picks
SportsLine's model is leaning Under on the point total, projecting the teams to combine for 65 points. The model also says one side of the spread hits in 60% of simulations. You can see the model's picks at SportsLine.
