![Detroit Lions vs Carolina Panthers Odds, Predictions and Best Bets for Week 16](/img/di/detroit-lions-vs-carolina-panthers-odds-predictions-and-best-bets-for-week-16-1.jpg)
Detroit Lions vs Carolina Panthers Odds, Predictions and Best Bets for Week 16
Detroit is a 2.5-point road favorite at Carolina in a match of teams that rarely meet. They have played only three times since 2014, with Carolina going 2-1 SU and ATS in those three. The Panthers shut out the Lions 20-0 in their most recent meeting on Nov. 22, 2020.
Carolina is 4-6 SU and 6-3 ATS since Steve Wilks replaced Matt Rhule as head coach…