Houston Astros at San Diego Padres odds, picks and best bets

The Houston Astros and San Diego Padres are playing interleague game at Petco Park at 9:10 p.m. ET.

Brandon Bielak is 3-0 with a 1.69 ERA and 1 WHIP in 21 1/3 innings for the Astros. Zach Davies is3-2 with 3.25 ERA in his last five starts this season. He hasn't allowed a home run in 19 innings since August 2 at Coors Field in Colorado.

Bielak has been impressive recently, especially last Monday, when he allowed just one earned run, one hit and four walks with four strikeouts in six innings in a win over the Colorado Rockies.

Davies will be facing his second straight American League West foe. He allowed three earned runs, three hits and two walks with six strikeouts in five innings against the Texas Rangers on Monday.

Houston Astros are playing San Diego Padres. Yordan Alvarez is out, Michael Brantley is questionable, Alex Bregman is injured, Chris Devenski is unavailable and Josh James is a doubt.

Francisco Mejia, Tommy Pham, Drew Pomeranz and Kirby Yates are injured.

The Padres won the series opener 4-3. They have won five consecutive games by a combined score of 38-21. The Padres are averaging 7.6 runs per game during their five-game win streak. The best play in this game is the Under 9 (-110). A $10 bet on San Diego will net a $7.75 profit if it wins, while a winning $100 bet is a profit of $11.50.