Indiana vs Ohio State Odds, Picks & Predictions

Ohio State is 9-0 and is the defending Big Ten champion. It was held to just 283 yards of offense at Northwestern last Saturday. The Buckeyes are a heavy favorite against Indiana. They are also the favorite to beat Michigan.

Ohio State Buckeyes are ranked No. 1 in both scoring offense and yards per play. They have a 41-point spread against Indiana, who have lost six straight games. The Hoosiers defense is bad, but the Buckeye offense will get picked apart. Ohio State has a lot of offensive weapons and will score at least 50 points. The team total is 48.5. It's a number they've gone Over in five of their last seven games and in four of the last five games with Indiana.

Indiana vs. Ohio State is a big game. The team total is over 48.5 (-113 at FanDuel).

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Indiana and Ohio State are playing a conference game. The Buckeyes are 4-4-1 ATS on the season but haven't covered since Week 8 against Iowa. Indiana is just 3-6 ATCW and its last cover came in Week 7.

Indiana is 5-4 to the Over thanks to its horrible defense. OSU is 6-3 to Over this season and had gone Over in six straight games before the Northwestern game last week. Indiana is averaging just 18.5 ppg over its last four games.

The Over is 5-0 in the last five meetings between Indiana and Ohio State.

Indiana vs Ohio State is a college football game.