Michigan vs. Indiana: Live stream, watch online, TV channel, prediction, pick, spread, football game odds

No. 4 Michigan Wolverines are undefeated after beating Colorado State, Hawaii and UConn. They have struggled in Big Ten play, losing to Maryland and Iowa. Indiana started the season 3-0, but has lost two straight games. The Hoosiers are playing at home this time.

Indiana beat Michigan 38-21 in 2020. It was the first time Indiana had beaten Michigan in football since 1987. Michigan has won 60 of 70 games against Indiana.

J.J., McCarthy has a top-five passing efficiency rating. Michigan has played in many blowouts to start the season. McCarthy is completing 78.6% of his passes for 10.1 yards per attempt with six touchdowns and no interceptions.

Indiana has lost 10 of 11 Big Ten games since the start of the 2014 season. The Hoosiers' 23-20 win over Illinois to open the season is the only Big League game they've won since. Their 10 losses have come by an average of 23.6 points.

Michigan vs. Indiana is live streaming on TV and online. The game is a pick-the-picks.

Michigan is favored by 22 points over Indiana. The game is being played at Michigan Stadium. The Wolverines defense struggled against Maryland, but the Terps' offense is more explosive. Indiana's offense hasn't shown much so far this season.