MLB Predictions & Odds 4/22/23

St. Louis Cardinals (8-11) vs. Seattle Mariners (8-11)
April 22, 2023 9:40 pm EDT
The Line: Seattle Mariners -155 / St. Louis Cardinals +135; Over/Under: +8
(Get latest betting odds)

The St. Louis Cardinals and the Seattle Mariners meet in MLB action from T-Mobile Park on Saturday. Let’s dive into the odds, starting pitching matchup, history and make a prediction for this game.

Odds

Seattle is a -155 home favorite while St. Louis is a +135 road favorite. The total for this game is set at 8 runs.

Starting Pitching Matchup

Miles Mikolas will start for St. Louis here and is 0-1 with an 8.10 ERA and 19 strikeouts this season. Seattle is sending Luis Castillo to the mound in this one and is 2-0 with a 0.73 ERA and 26 strikeouts this season.

Matchup History

Seattle’s 5-2 win over St. Louis was the first meeting between these two teams since 2019 and it snapped St. Louis’ two-game head-to-head win streak in this matchup.

Trends

St. Louis is 31-15 in their last 46 games against a team with a losing record and 0-5 in their last 5 games against the AL West while the under is 9-1-1 in their last 11 road games against a team with a right-handed starter. Seattle is 44-21 in their last 65 games against a team with a losing record and 22-8 in their last 30 home games against a team with a losing record while the over is 6-2-1 in their last 9 games against a team with a losing record.

Pick

I’m rolling with Seattle here. Miles Mikolas has had issues on the road going back to last season and while he gets the benefit of being in a pitcher’s park for this game, I still don’t have faith in him to be able to keep the Mariners at bay here. Luis Castillo has been rock solid so far this year and is not a pitcher I’m looking to fade right now. Give me the Mariners.