Oregon State vs. Colorado Prediction, Picks & Odds Week 10

We feel strongly about Beavers quarterback D.J. Uiagalelei's ability to be careful with the ball, and that belief shapes our prediction for the Oregon State vs. Colorado game, relying on the best college football odds available.

The Oregon State Beavers, holding a 6-2 record, are set to take on the Colorado Buffaloes, who stand at 4-4, in a Pac-12 matchup this Saturday. Both teams aim to secure a victory and bounce back from recent setbacks.

With Oregon State needing to cover a significant point spread as a nearly two-touchdown favorite in this matchup, the focus shifts to a player prop bet.

To accompany all of our college football predictions for Week 10 and our college football best bets, here is our best Oregon State vs. Colorado prediction and our college football picks (odds via our best college football betting sites; pick confidence based on a 1-to-5-star scale).

Oregon State vs. Colorado prediction: Week 10

D.J. Uiagalelei Under 0.5 interceptions (+100 via DraftKings) ⭐⭐⭐⭐

Betting on touchdowns and interceptions can always be a bit fluky, as you never know which way the ball is going to bounce on any given play. But we like this number on D.J. Uiagalelei to continue playing mistake-free football.

Uiagalelei has thrown four touchdowns on the year, with all four takeaways occurring during a three-game stretch against San Diego State, Washington State, and Utah. The Buffaloes' defense is not nearly as daunting as any of those units, however.

While two-way star Travis Hunter is capable of picking off an errant pass, Colorado ranks 91st (among 133 teams) in PFF's coverage grade. The Buffs have recorded 10 interceptions on the year, but I think that's only led to a nice number on this Under.

Uiagalelei hasn't thrown an interception in his last three games, and he likely won't be asked to do too much if Oregon State can jump out to an early lead. So, this seems like the best way of betting on a comfortable victory for the Beavers.

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Oregon State vs. Colorado best odds

This prop is only available at three of the best sportsbooks, with two of them offering the Under at +100. We played this at DraftKings due to the same-game parlay possibilities, as putting together an SGP involving Under 0.5 interceptions for Uiagalelei in an Oregon State win would make a lot of sense.

Oregon State vs. Colorado odds

The Beavers opened as 14-point favorites, but the market pushed the spread off a key number at our best sports betting apps. The total has seen plenty of movement, starting at 61.5 before climbing up to 62.5 as of this writing.

So far this season, Oregon State is 5-3 against the spread and 5-3 to the Over. Colorado is 4-3-1 ATS and 4-4 on closing point totals.

Oregon State vs. Colorado game info

• When: Saturday, Nov. 4 at 10 p.m. ET
• Where: Folsom Field, Boulder, CO
• How to watch: ESPN
• Weather: 48 degrees, 8-mph winds, 0% chance of precipitation

Oregon State-Colorado prediction made 11/02/2023 at 2:50 p.m. ET.

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