Padres vs. Cubs odds, tips and betting trends

On Wednesday, the San Diego Padres (12-13) are visiting the Chicago Cubs (13-9), at 7:40 PM ET, in the second game of a three-game set.

The Cubs are a tight favorite (-111 moneyline odds) when they meet the Padres (-108). The starting pitchers are Drew Smyly (2-1) for the Chicago Cubs, and Michael Wacha (2-1) for the San Diego Padres.

The Cubs defeated the Padres 6-0 yesterday, with Justin Steele getting the win (5.1 IP, 0 R, 3 H, 5 K) and Yan Gomes leading the way offensively (going 4-for-4 with a home run and three RBI). Blake Snell (5.0 IP, 2 R, 4 H, 5 K) took the loss for the Padres.

Before watching this Cubs vs. Padres matchup, here’s what you need to know about Wednesday’s action on the diamond, including viewing options.

Chicago Cubs vs. San Diego Padres Odds and Betting Lines

Tipico Sportsbook. Odds updated Wednesday at 3:21 PM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

• Favorite: Cubs (-111, bet $111 to win $100)
• Underdog: Padres (-108, bet $108 to win $100)
• Over/under: 8

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Cubs Stats and Trends

Cubs Betting Records

• This season, the Cubs have won eight out of the 12 games, or 66.7%, in which they’ve been favored.
• Chicago has a record of 8-2 in games when bookmakers favor them by at least -111 on the moneyline.
• The moneyline for this contest implies a 52.6% chance of a victory for the Cubs.
• Chicago’s games have gone over the total in 12 of its 22 chances.
• The Cubs are 14-8-0 ATS in their 22 games with a spread this season.

Drew Smyly (Cubs Probable Starter)

• The Cubs will send Smyly (2-1) to the mound to make his fifth start of the season. He is 2-1 with a 3.13 ERA and 23 strikeouts through 23 2/3 innings pitched.
• In his last appearance on Friday, the lefty threw 7 2/3 scoreless innings against the Los Angeles Dodgers while surrendering one hit.
• The 33-year-old has a 3.13 ERA and 9 strikeouts per nine innings across four games this season, while giving up a batting average of .195 to his opponents.
• Smyly is aiming for his fourth straight outing lasting five or more innings. He averages 5.8 frames per appearance on the mound.
• He will face off against a Padres offense that is batting .214 as a unit (30th in MLB). It is also slugging a collective .371 (24th in MLB) with 27 total home runs (16th in MLB).
• This season, the 33-year-old ranks 27th in ERA (3.13), 13th in WHIP (.913), and 31st in K/9 (9) among qualifying pitchers.

Cubs Batting Stats

• The Cubs have hit 29 homers this season, which ranks 10th in the league.
• Hitters for Chicago have a combined .446 slugging percentage this season, which ranks fifth in MLB.
• The Cubs rank second in MLB with a .278 team batting average.
• Chicago is among the highest-scoring teams in the majors, ranking fifth with 127 total runs this season.
• The Cubs are among the best in the league at getting on base, ranking second with an OBP of .351.
• Chicago ranks third in MLB in strikeouts per game with an average of 8.1 whiffs per contest.

Padres Stats and Trends

Padres Betting Records

• The Padres have been victorious in five, or 45.5%, of the 11 contests they have been chosen as underdogs in this season.
• San Diego has a win-loss record of 5-5 when favored by -108 or worse by oddsmakers this year.
• Bookmakers have implied with the moneyline set for this matchup that the Padres have a 51.9% chance of pulling out a win.
• San Diego and its opponents have gone over the total this season in 11 of its 25 opportunities.
• The Padres have posted a record of 12-13-0 against the spread this season.

Michael Wacha (Padres Probable Starter)

• Wacha makes the start for the Padres, his fifth of the season. He is 2-1 with a 7.08 ERA and 18 strikeouts in 20 1/3 innings pitched.
• The righty’s most recent time out was on Friday against the Arizona Diamondbacks, when he tossed four innings, surrendering five earned runs while allowing 10 hits.
• In four games this season, the 31-year-old has amassed an ERA of 7.08, with 8 strikeouts per nine innings. Opponents are batting .333 against him.
• Wacha has one quality start under his belt this season.
• Wacha has two starts this season that he pitched five or more innings.
• He will take the hill against a Cubs squad that is hitting .278 as a unit (second in the MLB). They are also slugging a collective .446 (fifth in the league) with 29 total home runs (10th in MLB play).

Padres Batting Stats

• The Padres rank 16th in baseball with 27 total home runs.
• So far this year, San Diego’s .371 slugging percentage ranks 24th in the majors.
• The Padres rank last in MLB with a .214 batting average.
• Averaging 3.7 runs per game (92 total), San Diego is the 24th-highest scoring team in baseball.
• The Padres are 26th in baseball with a .301 on-base percentage.

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• Game Day: Wednesday, April 26, 2023
• Game Time: 7:40 PM ET
• Stadium: Wrigley Field
• TV Channel: Marquee Sports Network
• Live Stream: Fubo (Watch for free)