Red Sox vs. Astros odds, prediction, line: 2022 MLB picks, Tuesday, May 17 best bets from proven model

The Houston Astros and Boston Red Sox are playing each other on Tuesday at 7:10 ET. The Red Sells won the first game 6-3 on Monday night. Boston is a money-line favorite at Caesars Sportsbook. Houston is an underdog at +105. SportsLine's advanced computer model simulates every MLB game 10,000 times and has returned over $300 for $100 players.

SportsLine's proven model has made its MLB picks and MLB predictions for Houston vs. Boston. Houston has won eight of last 10 games, but lost two of the last three. The money line is Houston -130, Boston -1.5, and the over-under is 8.

Red Sox are home favorites against Houston. Houston has won eight of last 10 games, but lost two of the last three.

Jose Altuve is a seven-time All-Star and former MVP. Michael Brantley is an elite hitter with a history of getting it done in the clutch for the Astros. Brantsley went 2-4 with double and a run scored on Monday.

Red Sox third baseman Rafael Devers is leading the league in hits with 47. Xander Bogaerts is hitting .346. Biaert's team is an offensive dynamo. Houston is a team with a winning record.