![49ers vs. Seahawks prediction, odds, line, spread: 2022 NFL picks, Week 2 best bets from proven computer model](/img/di/49ers-vs-seahawks-prediction-odds-line-spread-2022-nfl-picks-week-2-best-bets-from-proven-computer-model-1.jpg)
49ers vs. Seahawks prediction, odds, line, spread: 2022 NFL picks, Week 2 best bets from proven computer model
NFC West rivals are set to battle with the
Seattle Seahawks
and the
San Francisco 49ers
set to face off at 4:05 p.m. ET on Sunday at Levi's Stadium in Santa Clara. The Niners are looking to bounce back from a disappointing 19-10 Week 1 loss to the Chicago Bears, with the Seahawks are looking to build off their surprising 17-16 win over the Denver…