UNLV vs. San Jose State prediction, odds, spread: 2022 Week 6 college football picks, best bets by top model

San Jose State Spartans host UNLV Rebels at CEFCU Stadium on Friday at 10:30 p.m. ET. San Jose is 3-1 this season, while UNL is 4-0. Caesars Sportsbook lists the Spartans as 6.5-point home favorites. The total number of points Vegas thinks will be scored is 52. SportsLine's advanced computer model simulates every FBS college football game 10,000 times and has returned a profit of more than $3,100 for $100 players on its top-rated college game picks against the spread.

UNLV is 4-1 against the spread in 2022. San Jose State is 3-0 against spreads this season. SportsLine's model has made its picks and CFB predictions for UNLV vs. SJSU.

UNLV vs. San Jose State is a 2022 Week 6 college football game. The Rebels are 4-1 against the spread in 2022. SJSU is 3-0 against spreads this season.

UNLV's offense is keyed by high-end talent at the skill positions. Doug Brumfield is leading the Mountain West with eight touchdown passes and 1,223 passing yards this season. Aidan Robbins leads the conference with 8 rushing touchdowns and is No. 2 in the league with 506 rushing yards. Ricky White is third in conference in receiving with 360 receiving yards and three touchdown catches. UNLV is averaging 37.8 points per game this year.

San Jose State is scoring 26.0 points per game and second in the Mountain West in total offense (367.5 yards per contest) and passing offense. The team is also No. 2 in defense, giving up only 15.8 points and 310 yards a game. UNLV has allowed the second-most sacks of any team in Mountain WIll this season.

SportsLine's model is leaning Over on the total. Both teams are projected for more touchdown passes than interceptions. One side of the spread hits in more than 60% of simulations.