USC vs. Nevada odds, line: 2023 college football picks, Week 1 predictions from proven model

The No. 6 USC Trojans will be eyeing another blowout victory when they host the Nevada Wolf Pack on Saturday. USC was one of 14 FBS teams to play in Week 0, cruising to a 56-28 win over San Jose State. Nevada is getting set for its season opener after going 2-10 and finishing at the bottom of the Mountain West Conference West Division last year. 

Kickoff is set for 6:30 p.m. ET on Saturday at United Airlines Field at the Los Angeles Memorial Coliseum. The Trojans are favored by 38 points in the latest USC vs. Nevada odds, while the over/under is set at 66.5 points, per SportsLine consensus. 

Before entering any USC vs. Nevada picks, you NEED to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model has simulated USC vs. Nevada 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread has all the value. You can only see the pick at SportsLine.