Week 15 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay pays 25-1

The Philadelphia Eagles are 9-point favorites against the Chicago Bears in the latest NFL odds at Caesars Sportsbook. The Eagles have won four straight games. SportsLine's advanced computer model simulates every NFL game 10,000 times and has made some impressive bets in recent weeks. It is targeting a 25-1 payout for parlaying its best bets for Week 15. It has beaten 94% of CBS Sports Football Pick'em players four times in a row.

The model simulates every game 10,000 times and it's high on the Dallas Cowboys to cover against the Jacksonville Jaguars. The Cowboys have two strong running backs, Ezekiel Elliott and Tony Pollard. Their rushing attack has helped Dallas gain 144.5 yards on ground per game.

The advanced model predicts a five-way football parlay that pays 25-1. It also has a pair of underdogs that have a chance to win outright.