Week 3 college football ATS betting picks and predictions: Houston, Cincinnati and Notre Dame claim double-digit victories

Week 3 of the college football season is here. There are some high-quality games between unranked schools. The betting leans for a good chunk of this Saturday's televised slate.

This weekend's games are against teams ranked outside the AP Top-25. Notre Dame takes on Drew Pyne at quarterback. Kansas can get to 3-0 with a win over Houston.

Louisville and Florida State are playing each other tonight at 7:30 p.m. (ESPN). The game is a good chance for Florida to win. The Seminoles have made progress in Mike Norvell's third season.

Florida State is a two-point favorite against Houston.

Wyoming is a two-point favorite against Air Force. The Cowboys' offense will keep the game within two touchdowns.

Wyoming is a favorite to win over 15 points.

Syracuse is 2-0 and Purdue is 1-1. The Boilermakers should win on the road.

Houston, Cincinnati and Notre Dame all won double-digit games in the last week. Purdue is a one-point favorite against the spread.

Cincinnati is the favorite to win the American this season. The Bearcats beat Miami Ohio 4-plus TD on Saturday.

Houston, Cincinnati and Notre Dame won double-digit victories in the last week. Cincinnati is a favorite at -22.

Indiana is favored to beat Western Kentucky. Connor Bazelak will make plays with his arm on crucial down and distances.

Week 3 college football ATS betting picks and predictions: Houston, Cincinnati and Notre Dame claim double-digit victories.

UCLA is 3-0 after a cupcake non-conference schedule. They beat USA. UCLA plays South Alabama at 2 p.m. on Saturday.

Houston, Cincinnati and Notre Dame won double-digit games in the last week. UCLA is a favorite at -15.5.

Virginia lost 24-3 to Illinois. Old Dominion's Hayden Wolff will be able to keep the Monarchs within the spread.

Old Dominion is a favorite at +9.5.

Notre Dame is looking for its first win of the season. Drew Pyne will start at quarterback for the Fighting Irish. They are 11-points underdogs against California.

Houston, Cincinnati and Notre Dame all won double-digit games in the last week. Notre Notre Irish is a -11 favorite.

Northern Illinois is a favorite against Vanderbilt. The Commodores' quarterback Mike Wright will be looking to bounce back after being benched in the Commadores loss to Wake Forest.

Houston, Cincinnati and Notre Dame all won double-digit games in the last week. Vanderbilt is a favorite at +2.5.

Minnesota and Colorado are playing each other on Saturday at 3:30 p.m. Colorado is a four-TD underdog. Minnesota has a chance to win the Big Ten West.

Colorado is a favorite to cover at +27.5.

Wisconsin lost to Washington State 17-14. Wisconsin is looking to bounce back against New Mexico State.

Wisconsin is a favorite to cover at Wisconsin -37. Houston, Cincinnati and Notre Dame won double-digit.

Houston and Kansas are playing each other in 2022. Houston is favored by double-digit points. Kansas is averaging 55.5 points through its first two games.

Houston, Cincinnati and Notre Dame are all favored to win this week.

Washington State beat Wisconsin 17-14 on Saturday. The game is at 5 p.m. Pacific time. Cam Ward will play well for Washington State.

Washington State is a favorite at 16.5 against the spread.

LSU is a home underdog against Mississippi State. The Tigers won their first game of the Brian Kelly era against Florida State 65-17.

LSU is a two-point favorite against the spread.

Iowa is a heavy favorite against Nevada. Nevada's offense has been poor so far this season. Iowa might only need a field goal to cover the spread.

Nevada is a favorite to win the game.

Maryland plays SMU in College Park at 7:30 p.m. on Saturday. The game will be watched by Taulia Tagovailoa and Tanner Mordecai.

Houston, Cincinnati and Notre Dame all won double-digit games in the last week. SMU is a favorite at +3.5.

FAU and UCF are playing each other tonight at 7:30 p.m. on CBSSN. FAU's defense will limit John Rhys Plumlee and the Knights' offense on early downs.

FAU is a favorite to win over 9 points.

Arizona State is the favorite against Eastern Michigan. The Sun Devils lost to Oklahoma State last week.