49ers Vs Cardinals Monday Night NFL Picks & Predictions: Odds Continue To Climb Ahead Of Kickoff

The NFL heads south of the border for a high-altitude matchup in Mexico City’s Estadio Azteca. The San Francisco 49ers face off against the injury-ridden Arizona Cardinals. Early lines had San. Francisco listed as the -4.5 point favorites ahead of Week 10”s conclusion. Now the odds extend as far as -8.

49ers are -450 and the Cardinals are +360.

49ers are -10. Cardinals are +10 ahead of Monday Night NFL game.

49ers and Cardinals are playing on Monday Night NFL. The Cardinals won the last game against the Rams 27-17. Colt McCoy is the backup quarterback for the Cardinals. DeAndre Hopkins and Marquise Brown are injured. San Francisco's defense ranks 5th in EPA allowed per play. 49ers' pass rush ranks fifth. Cardinals will have to limit turnovers to win the game. The game is expected to be close. It's a divisional game between two good teams. They play each other. A late turnover could be the difference between winning and losing.