Cardinals vs. Pirates odds, line, prediction: 2022 MLB picks, April 11 best bets from proven computer model

The St. Louis Cardinals (2-1) host the Pittsburgh Pirates (1-2) on Monday afternoon. The Cardinals won the first two games of the series before Pittsburgh won in the last game. Right-hander Dakota Hudson will start for St Louis and Zach Thompson will make his season debut for Pittsburgh.

SportsLine's computer model has picked St. Louis Cardinals vs. Pittsburgh Pirates. The Cardinals are favored by 180 points. Pirates are +160. Cardinals went 45-36 at home last season.

St. Louis Cardinals and Pittsburgh Pirates are playing each other. The Cardinals are -180, Pittsburgh is +160. Cardinals won 45-36 at home last season, while Pirates won 24-57 on the road.

Paul Goldschmidt has a good batting eye and good defense. Nolan Arenado has natural home-run power and displays great range from third base. Last season, the six-time All-Star hit 34 home runs and batted in 105 runs.

Bryan Reynolds hasn't had the start he hoped for but is still a terrific player. Ke'Bryan Hayes has played fairly well in this series. He has two hits in consecutive games and has a batting average of .400.

SportsLine's model is leaning over on the run total. It also says one side of the money line has all the value.