Chiefs vs. Chargers predictions: Week 11 NFL picks, odds

The Chiefs are looking to extend their three-game winning streak when they visit the Chargers on Sunday at 8:20 p.m. ET. The game features All-Pro candidates in Kansas City quarterback Alex Smith and LA running back Austin Ekeler.

Kansas City is in the driver's seat to win the AFC West again. The Chargers are in second place in their division and need a win to bolster their hopes of making the playoffs.

The Chargers need to win this game more than the Chiefs to go to the playoffs. A loss would drop Los Angeles to 5-5 and they would be in a blender with the Patriots and Bengals. The last time the Chargers and Chiefs played, Los Los lost it on a pick-six and a pair of field goals. Four of the last five games between the teams have been decided by six points or less. Los LA has a winning record against the spread this season, going 6-3.

The over-under for the game is 51 points. The last time the teams played each other, the score was 27-24. Both teams are struggling with injuries. Caesars Sportsbook recommends picking the Chiefs to win the under 51-point game.

The Chiefs haven't scored on their opening drive since their win in Tampa Bay on October 2. Caesars Sportsbook has a prop for the Chiefs' first drive: +113 they punt, +200 they score a touchdown, -400 for a field goal attempt, and +575 for turnover. The Chiefs have turned the ball over on opening drives in three of their last four games. Los Angeles has an opportunistic defense, but it has only 12 takeaways this season.