College Football Odds: USC vs. Arizona prediction, odds and pick

USC's last game outside the Los Angeles metro area is against Arizona. Eric Gentry, the team's best linebacker, will be a game-time decision. Arizona's defense is porous, but the Wildcats have a chance at the upset. Arizona quarterback Jayden de Laura is talented and can score a lot of points. The Wildcats' offense has scored 39 points in their last two games. USC's defensive team is in need of improvement after giving up 43 points to Utah two weeks ago. It's also in desperate need to improve its defense after allowing 49 points three of last four games, including against Washington Huskies.

USC has regularly been scoring over 40 points this season. Arizona has allowed close to 50 points in Pac-12 games this year. USC might enter this game intent on scoring 56 points. If they do score 56, Arizona would need to score 41 to cover.

Arizona can cover the spread against USC. Arizona coach Jedd Fisch has had two weeks to look at USC film and find the points of weakness in this USC defense.

USC's offense will win the game, but Arizona's defense will keep Arizona in the hunt. USC will score 49 points, while Arizona will probably score close to 40.

Arizona is favored by 15.5 points over USC.