College football situational betting spots for Week 1

There are 18 FBS teams in action in Week 1. There are some interesting early-season matchups. The game card is interesting. The team that looks better prepared than the other one is better bettors.

Virginia Tech Hokies travel to Norfolk to play Old Dominion Monarchs on Friday. The Monarchy won the last game there 49-35. The Hokie's new head coach Brent Pry is in a state of flux.

Illinois beat Wyoming last week. Indiana has a new starting quarterback and a lot of changes after finishing last season with eight straight losses. The Hoosiers are getting a field goal.

Utah Utes are playing at Florida Gators on Saturday. The weather conditions are muggy and the game is in the mid-80s. BYU is playing USF in Tampa.

Georgia State Panthers are playing at Williams-Brice Stadium for the first time. The game is important to head coach Shawn Elliott.

Memphis Tigers and Mississippi State Bulldogs are playing each other on Saturday. Memphis won the last season's game 31-29. The Bulldogs outgained Memphis by 222 yards and had the ball for more than 40 minutes.

Florida State Seminoles vs. LSU Tigers is a neutral-site game played on a Sunday. It will be Brian Kelly's first game as the head coach for LSU. The game is played in New Orleans.

South Dakota State Jackrabbits play Iowa Hawkeyes in the first game of the college football season. The Jacks lost in two playoff semifinals last season and in 2020 to Sam Houston State. Iowa plays Iowa State next week in their annual CyHawk Trophy rivalry game.