College Football Week 10 Best Bets, Odds & Predictions

Georgia is a co-favorite in the College Football Championship Game of the Year with Ohio State. The No. 1 Bulldogs are about to get their toughest test yet in an epic home matchup with No 2 Tennessee. No 6 Alabama plays No 15 LSU and No 5 Clemson plays Notre Dame on Saturday.

College Football Week 10 is in the air. There are some interesting betting lines for the games.

TCU is 8-0 for the first time since 2015. They are a single-digit favorite against Texas Tech. TCU has the fourth-best offense in the nation. TexasTech has scored at least 38 points in every game this season.

Tennessee and Georgia are playing each other on November 5 at 3:30 p.m. ET. It's the third time since 2010 that the No. 1 and No 2 teams will meet in the regular season.

Oklahoma State lost 48-0 at Kansas State. The Cowboys are on the road at the Memorial Stadium this weekend. Kansas has lost three straight games after a 5-1 start.

Alabama and LSU are playing each other in the first game of the week at 7 p.m. ET. First place in SEC West is at stake for the rivals.

Texas and Kansas State are playing each other on November 5 at 7 p.m. ET. The Wildcats are 6-2 on the year and one game behind TCU in the Big 12 standings. Texas lost at Oklahoma State two weeks ago.

Clemson and Notre Dame will play each other on November 5 at 7:30 p.m. ET. The teams played each in a two-game series in 2020. Notre Notre beat Clemson 47-40 in South Bend. Clemson won the ACC title game 34-10.

Michigan is 8-0 and has a looming date with No. 2 Ohio State on November 26. Michigan is a massive favorite against Rutgers. Rutgers is not as good as Michigan, but it's a relatively strong defense.

Wake Forest and North Carolina State are playing a close game on November 5 at 8 p.m. ET. The winner will move to 2-3 in the ACC and out of contention.