Hornets vs. 76ers odds, line, spread: 2022 NBA picks, Nov. 23 predictions from proven computer model

Hornets host 76ers on Wednesday at 7 p.m. ET. Charlotte has lost 11 of its last 12 games. Philadelphia has won four of last five games, including a 115-106 victory over Brooklyn on Tuesday. The Hornets are favored by 4.5 points.

SportsLine's computer model has set its sights on Hornets vs. 76ers. The model is using its advanced computer simulations to pick the winner.

Hornets vs. 76ers is a 2022 NBA game. The Hornets are favored by 4.5 points.

Joel Embiid, Tyrese Maxey and James Harden are injured for the 76ers. Tobias Harris (15.3), De'Anthony Melton (10.4) and Dennis Smith Jr. (4.0) are the only other players averaging double figures. Charlotte is well-rested coming into the game, having just had its first two-day break since Oct. 24-25.

Philadelphia beat Brooklyn without its top three scorers on Tuesday. LaMelo Ball is injured for Charlotte. The Hornets have lost 11 of their last 12 games. Charlotte has covered the spread three times in its last twelve games and failed to cover in five straight home games recently.

The model simulates 76ers vs. Hornets 10,000 times and it's leaning Over. It also generated a point-spread pick that's hitting in well over 50% of simulations.