Michigan vs. Penn State odds, line: 2022 Week 7 college football picks, predictions from proven model

No. 5 Michigan Wolverines take on No. 10 Penn State Nittany Lions in Ann Arbor on Saturday. The Wolverine's are 7-point home favorites. Both teams are unbeaten this season. SportsLine's computer model simulates every FBS college football game 10,000 times. It has generated a profit of almost $3,300 for $100 players on its college game picks against the spread.

Michigan and Penn State are playing each other in the college football game on Saturday. The game is a favorite for Michigan. SportsLine's computer model has made its picks and CFB predictions for the game.

Michigan vs. Penn State is a Week 7 college football game. The Wolverines are 3-3 against the spread this season.

Penn State is playing well to begin the 2022 season. The Nittany Lions are averaging 443.6 yards per game. Penn State's quarterback is Sean Clifford, who has 13 touchdowns and only two interceptions in 2022. On defense, Penn state is limiting opponents to 14 points or fewer.

Michigan is putting up 43.0 points per game and 458.7 yards per contest. The Wolverines have 20 rushing touchdowns with 5.4 yards a carry. Michigan's offensive line is performing well. Blake Corum is in the top three of the country in rushing yards (735) and rushing TDs (11).

SportsLine's model is leaning Over on the total and projects 54 combined points for Penn State and Michigan. One side of the spread hits almost 60% of time.