Minnesota vs. Purdue prediction, odds, spread: 2022 Week 5 college football picks, best bets from proven model

Minnesota Golden Gophers are 9-point favorites against Purdue Boilermakers. The game is scheduled for noon on Saturday. Minnesota leads the all-time series 20-13. In 2021, Minnesota beat Purdue 20 to 13. SportsLine's college football model has generated a profit of more than $3,100 for $100 players on its top-rated college game picks.

Minnesota and Purdue are playing each other in college football. The game is a straight-up bet between Purdue and Minnesota. Minnesota is 4-0 ATS in their last four games in October.

Minnesota and Purdue are playing in the Week 5 college football game. The over/under is 53 points. Minnesota is a favorite at -350 and the money line is -275.

Tanner Morgan is the quarterback for Minnesota. Mohamed Ibrahim is second in the nation in rushing yards (567) and rushing touchdowns (8). Minnesota's offensive line is dominant. Minnesota is first in conference in running yards per game (294.5).

Dylan Downing is the team's leading rusher with 204 yards and two touchdowns. Payne Durham is a tight end who is second on the Boilermakers in receptions (17), receiving yards (150), and touchdowns (2).

SportsLine's model is leaning Over on the total. The model also says one side of the spread hits more than 50% of time.