Ohio State vs. Michigan prediction, odds, line: 2022 Week 13 college football picks, best bets by proven model

The winner of The Game earns a trip to the Big Ten Championship Game and an inside track at the College Football Playoff. The Buckeyes are favored by 8 points in the latest Caesars Sportsbook odds. Michigan running back Blake Corum is expected to play despite a knee injury. SportsLine's proven computer model simulates every FBS college football game 10,000 times and returns a huge profit for its players.

Ohio State and Michigan are playing each other in the Week 13 college football game. The Wolverines are 5-1 against the spread in their last six road games and 4-0-2 ATS in last five home games. SportsLine's computer model has picked Michigan and Ohio State.

Ohio State is favored by 8 points against Michigan. The Wolverines are 5-1 against the spread in their last six road games. Ohio State's home team is 4-0-2 ATS in its last five home games against teams from Michigan and Ohio.

Miyan Williams is the team's leading rusher with 783 yards and 13 touchdowns. He missed last week's game with a lower leg injury. Treveyon Henderson and Dallan Hayden are also running backs for the Buckeyes. Henderson has carried 107 times for 571 yards (5.3 average) and six touchdowns, and Hayden has 100 carries for 503 yards.

Ronnie Bell is the top receiver for Michigan. He has 48 receptions for 641 yards and two touchdowns this season. Cornelius Johnson has 25 receptions, 300 yards (12.0 average) and four touchdowns. Bell has played in 43 career games with 28 starts.

SportsLine's model is leaning Over on the total. It projects a combined 65 points for Michigan and Ohio State. One side of the spread hits in well over 50% of simulations.