Pro Picks leans toward Broncos to kick off Week 5
Denver Broncos and Indianapolis Colts are playing a game on Thursday night. Denver lost Javonte Williams to a season-ending knee injury. Jonathan Taylor is injured. The Broncos are three-point favorites. Pro Picks leans toward the home team. It's been 20-12 against the spread over the past two weeks. They went 20/12 in the last two games. Matt Ryan has nine fumbles and five interceptions in four games for the Colts.
Los Angeles Chargers are at home against Cleveland. The Broncos are favored to win.
Pro Picks leans toward Broncos to kick off Week 5. Philadelphia (4-0) is the only undefeated team in the NFL. Arizona (2-2) hasn't scored a point in first quarter and is 9-16-1 at home under Kliff Kingsbury.
New York Giants (3-1) and Green Bay (2-3) are playing in London. The Giants have some QB injury concerns.
Pro Picks leans toward Broncos to kick off Week 5. Tennessee (2-2) at Washington (1-3) is a must-win for the Titans.
Seattle (2-2) is rolling on offense behind Geno Smith, but their defense is struggling. New Orleans (1-3) nearly beat Minnesota without Jameis Winston, Alvin Kamara and Michael Thomas.
Pittsburgh (1-3) is at Buffalo (3-1). The Steelers lost to the Jets last week. Josh Allen and the Bills won their first game after seven straight defeats.
Pro Picks leans toward Broncos to kick off Week 5. Chicago (2-2) is at Minnesota (3-1) and the Bears need to get their pass game going.
Denver Broncos take on the Vikings in the opening game of the NFL season. Houston takes on Jacksonville.
Miami (3-1) plays New York Jets (2-2) in the first game of the week. Teddy Bridgewater makes his first start for the Dolphins. Zach Wilson tries to get the Jets to their first 3- 2 start since 2017.
Detroit (1-3) is at New England (2-1) in a game that features Zappe. The Patriots are using Zapke because Mac Jones has an ankle injury and Brian Hoyer has a concussion. Detroit is allowing a league-high 444.8 yards and 35.3 points per game.
Pro Picks leans toward Broncos to kick off Week 5.
The 49ers (2-2) need to avoid a letdown against the struggling Panthers (1-3) in Week 5.
Denver Broncos will play at home against San Francisco 49ers. Dallas Cowboys will take on Los Angeles Rams.
Cincinnati (2-2) is coming off extra rest after Joe Burrow led the defending AFC champs to two wins in five days. Baltimore ( 2- 2) would be unbeaten if they could protect double-digit second-half leads at home.
Las Vegas (plus 7 1/2) at Kansas City. The Chiefs (3-1) have won seven of eight at home over the Raiders (1-3).
