Seahawks-49ers NFC Wild-Card odds, spread, lines and best bet

The second-seeded 49ers (13-4) host NFC West division rival and the seventh-seed Seahawks (9-8) on Saturday afternoon. The Niners were favored and easily covered the spread in both regular-season games. San Francisco is on a 10-game winning streak and will be looking to make it 11 on the road. Seattle exceeded expectations this season after trading Russell Wilson to Denver. Seattle's defense struggled versus the run this year, allowing 150.2 rushing yards per game and 25.6 points per match.

Seahawks are 9-8 straight up and 7-10 against the spread.

Seahawks and 49ers are playing in NFC Wild-Card game. San Francisco is 7-1 against the spread as a home favorite. Seattle is 3-3 as an away underdog. The 49er's games have gone over nine times this year, while Seattle's have only gone under eight times.