Baltimore Orioles at Toronto Blue Jays odds and predictions

The Baltimore Orioles (29-16) play the middle contest of a 3-game series with the Toronto Blue Jays (25-20) Saturday at Rogers Centre. First pitch is scheduled for 3:07 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Orioles vs. Blue Jays odds and make our expert MLB picks and predictions for the best bets.

Season series: Orioles lead 1-0; Blue Jays won the season series 10-9 in 2022

The Orioles posted a 6-2 win in Friday’s series opener as a moderate underdog (+145) as the Under (9) cashed. Baltimore has won 3 of its last 4 games and has averaged 5.2 runs per game (RPG) across its last 5 outings.

The Blue Jays have dropped 4 of the past 5 games overall, while the Under has connected in 3 in a row. Toronto is just 1-8 in its last 9 games inside the AL East.

Orioles at Blue Jays projected starters

RHP Grayson Rodriguez vs. RHP Alek Manoah

Rodriguez (2-1, 6.57 ERA) makes his 9th start. He has a 1.73 WHIP, 4.1 BB/9 and 10.7 K/9 in 37 innings.

• Last start: Loss, 3 1/3 IP, 8 ER, 9 H, 3 BB, 3 K in a 9-5 home loss vs. the Los Angeles Angels Monday
• Road splits this season: 1-0, 5.79 ERA (18 2/3 IP, 12 ER), .270 OBA in 4 starts

Manoah (1-4, 5.40 ERA) makes his 10th start. He has a 1.80 WHIP, 6.4 BB/9, 7.0 K/9 in 45 IP innings.

• Last start: Loss, 4 IP, 5 ER, 6 H, 7 BB, 3 K in a 7-4 home loss vs. the New York Yankees Monday
• Home splits this season: 0-2, 8.50 ERA (18 IP, 17 ER), .333 OBA in 4 starts

Orioles at Blue Jays odds

BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:30 a.m. ET.

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Orioles at Blue Jays picks and predictions

Prediction

Orioles 7, Blue Jays 5

The ORIOLES (+125) are worth playing as underdogs in this middle game.

The O’s have won 4 of the past 5 games inside the division while going 10-4 in the past 14 games on the road. Baltimore is also 5-2 in the past 7 against a right-handed starting pitcher.

The Jays have won just once in the past 5 home games and have cashed just 1 of the previous 9 games against AL East foes.

The ORIOLES +1.5 (-150) aren’t priced out of line if you’d like an insurance run and just can’t bet them straight up.

Baltimore is 3-2 in the past 5 on the run line as an underdog, while winning 3 of those games outright, including Friday’s outing.

The Blue Jays have failed to win each of the past 4 games as favorites and are 0-5 in their last 5 on the run line as favorites.

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The OVER 9.5 (-105) is worth a look with 2 very giving pitchers on the bump.

The Under cashed on Friday night, but the Over is 9-3-2 in the past 14 meetings between these clubs in Toronto and is 33-16-7 in the past 56 meetings overall in this series.

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