Chiefs vs. Colts Prediction and Best Bets (NFL Week 3)

The Kansas City Chiefs have won their first two games of the season. The Buffalo Bills have already won two of their games. They beat the Rams and Titans. Indianapolis has lost both of its games this season, including a 0-0 tie in Houston.

Kansas City Chiefs are 2-0 and 1st in the AFC West. Indianapolis Colts are 0-1-2 and 3rd in AFC South. The game is on Sunday, September 25, 2022 at 1:00 p.m. Eastern Time. It's being broadcast on CBS.

Kansas City Chiefs (2-0) play Indianapolis Colts (0-1-2) on Sunday, September 25th at 1:00 p.m. Eastern Time. The game will be broadcast on CBS.

Chiefs vs. Colts is a game in NFL Week 3. Chiefs are -5.5 (-112) and Colts are +5%.

Chiefs vs. Colts is a game in NFL Week 3.

The Colts lost to the Jaguars. Matt Ryan was sacked five times and the team was outgained 517-299. The team has won just two games in a row. They have lost eight straight at home to Jaguars, who have improved under Doug Pederson. The game ended in the Colts favor. Frank Reich's team is going to need to improve to beat the Chiefs.

The Chiefs are 2-0 after a miracle comeback win in Baltimore last Sunday. Patrick Mahomes has completed 73 percent of his passes for 595 yards and seven touchdowns. Travis Kelce has 16 catches for 172 yards. The Chiefs have run the ball well, averaging 4.9 yards per carry through the first two games. Colts' defense hasn't been terrible by any stretch, but it didn't stop young signal-callers Davis Mills and Lawrence.