Clemson vs. Syracuse odds, prediction, betting trends for ACC showdown

No. 14 Syracuse takes on No. 5 Clemson in a battle of undefeated ACC teams at Memorial Stadium in Clemson, S.C. on Saturday at 12 p.m. ET. Game will be televised on ABC. Syracuse is the only unbeaten team in the FBS. Clemson is unbeaten and has won 37 straight home games.

Clemson is favored by 13.5 points. The over/under is 51. Syracuse is a +550 favorite.

Syracuse is 5-1 ATS this season. The Orange are 4-2 AET against Clemson under Babers. Clemson is 4th in the ACC this year and has covered in last three games.

Clemson and Syracuse are two of the best run defenses in the ACC. Syracuse limited Clemson to 116 yards on 3.1 yards per carry in last year's game. Clemson is better against the run this year. DJU has been fantastic for the Tigers over that four-game stretch in ACC, but he's also a rushing threat. Ordonde Gadsden II is the Orange's leading receiver with 507 yards and five touchdowns.

Clemson has seven receivers with at least 10 catches. Antonio Williams has 24 catches, 334 yards, 2 TDs and Beaux Collins 18, 290 yards. Jake Briningstool has scored TDs in each of his last three games. Syracuse faces a challenge knowing that balance factor in Clemson’s offense.

Syracuse will try to control the clock with Tucker and their defense. Clemson's offense converts 50.5% of the time. Will Shipley scored on a run and a catch last year.