No. 7 Penn State vs. No. 24 Iowa odds, line: Proven model reveals college football picks for Week 4, 2023

The Big Ten on CBS schedule includes seven games in 2023 and that includes a marquee matchup between the Penn State Nittany Lions and Iowa Hawkeyes on Saturday. Penn State is ranked No. 7 in the AP Top 25 after a 3-0 start while Iowa is also 3-0 and ranked 24th in the Week 4 college football polls. The two programs didn't play each other last season but Iowa won head-to-head matchups over Penn State in 2021 and 2020, covering the spread as favorites on both occasions.

However, this time around it's the Nittany Lions who are favored by 14 points at home in the Penn State vs. Iowa odds from the SportsLine consensus while the over/under is down to 38.5. Kickoff is scheduled for 7:30 p.m. ET on Saturday at Beaver Stadium in State College, Penn. (See up-to-date odds for every game this week on our college football odds page.) 

Saturday's game can be seen live on CBS and streamed live on Paramount+, which you can now try free for the first seven days when you .

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Before making any Iowa vs. Penn State picks or college football predictions, see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a stunning profit of almost $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows that Penn State is a perfect 3-0 against the spread to start the season thanks in large part to a defense that has been dominant. The Nittany Lions are only allowing 267.3 yards and 11.7 points per game despite two of their three games being played against Power Five opponents (West Virginia and Illinois). 

However, the Hawkeyes have been nearly as good on that side of the ball, allowing only 286.0 and 12.3 points per game in wins over Utah State, Iowa State and Western Michigan. Iowa has several defensive starters who were with the program when it last visited State College, capturing a 41-21 victory as 1-point favorites on the road in 2020. 

Now, the model has set its sights on Penn State vs. Iowa. We can tell you it is leaning Over the total, and it also says one side of the spread hits in more than 50% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.