Ole Miss vs. Mississippi State prediction, odds: 2022 Egg Bowl picks, college football bets from proven model

Ole Miss Rebels take on the Mississippi State Bulldogs in the annual Egg Bowl on Thanksgiving night at 7 p.m. ET. Ole Miss is 8-3 overall and 4-2 in SEC play this season. Mississippi is 7-4 overall, 3-5 against SEC teams. Caesars Sportsbook lists Ole Mississippi as a 2-point home favorite. The over/under is 59 in Vegas. SportsLine's advanced computer model simulates every FBS college football game 10,000 times and has returned a huge profit for its players.

SportsLine's proven model has set its sights on Mississippi State vs. Ole Miss in 2022. The model is using its advanced stats to make its picks. There are several college football odds and betting lines for Ole Mississippi vs Mississippi.

Ole Miss and Mississippi State are playing in the 2022 Egg Bowl. The Bulldogs are 5-5-1 against the spread this season. Ole Miss is 4-6-2 against spreads this year.

Mississippi State has a strong defensive resume this season. The Bulldogs are yielding only 24.4 points per game in 2022. They are above-average in the SEC in giving up only 351.7 total yards per games. Emmanuel Forbes is a standout in their secondary with six interceptions.

Ole Miss has won the last two games in the rivalry. The Rebels are excellent on offense under Lane Kiffin. Ole Miss is No. 4 in total offense, averaging 505.5 yards per game. They have the SEC's best rushing offense.

SportsLine's model is leaning Under on the total, projecting 57 combined points for Ole Miss vs. Mississippi State in 2022. One side of the spread hits in over 60% of simulations.