Steelers vs. Saints prediction, odds, line, spread: 2022 NFL picks, Week 10 best bets from proven model

Andy Dalton and the New Orleans Saints are on the road to take on Kenny Pickett and Pittsburgh Steelers. Kickoff is at 1 p.m. ET. New York is favored by 1 point in the latest Steelers vs. Saints odds. The over/under is set at 39.5. SportsLine's simulation model simulates every NFL game 10,000 times and has returned over $7,500 for $100 players on top-rated NFL picks since its inception.

SportsLine's computer model has set its sights on Steelers vs. Saints and has made its picks and NFL predictions. Pittsburgh is favored by 1 point.

Steelers vs. Saints is a game with a total score of 39.5 points. Pittsburgh is the favorite by one point.

Pittsburgh Steelers are in the bottom-10 of the NFL in every major offensive statistic. The team's per game average of 15.0 points is disappointing. Rookie quarterback Pickett has shown glimpses of high-level play. Outside linebacker T.J. Watt has missed most of this season with a chest injury. He may make his return against the Saints.

The Saints lost 27-13 to the Ravens this past Monday. They are still alive in the NFC South, but they can't afford many more losses. New Orleans will get back veteran receiver Jarvis Landry, who has been out since Week 4 with an ankle injury.

The model simulates Steelers vs. Saints 10,000 times and it has picked the Steelers to win. The model is leaning Over on the point total and says one side of the spread hits over 50% of time.