Saints vs. Seahawks prediction, odds, line, spread: 2022 NFL picks, Week 5 best bets from advanced model

Saints vs. Seahawks is a 2022 NFL game. Seattle is coming off a thrilling 48-45 shootout win over the Detroit Lions. New Orleans is 1-3 against the spread in 2022. Andy Dalton will start for New York after Jameis Winston was ruled out. The over/under is set at 45. SportsLine's advanced model simulates every NFL match 10,000 times and has returned a huge profit for its players.

Saints vs. Seahawks is a Week 5 NFL game. The game is currently being played at the Superbowl XLIV XLVIII XLVII. There are several NFL odds and betting lines for Saints vs Seahawks.

Saints vs. Seahawks is a game with a total of 45 points.

The Saints lost 28-25 to the Vikings in London. New Orleans has been inconsistent in the last four weeks. The Saints have a problem with ball security and are last in turnover percentage. They are the more talented team in this matchup. They have lost three games in a row.

Geno Smith has been impressive for Seattle this season. The quarterback has completed 77.3% of his passes for 1,037 yards, six touchdowns, two interceptions and a quarterback rating of 108.0. Rashaad Penny is averaging 6.5 yards per carry for the season, which ranks seventh in the NFL.

The model simulates Saints vs. Seahawks 10,000 times and it has generated a point-spread pick that is hitting in over 50% of simulations.