Top College Football Moneyline Bets for Week 5: Will Kansas Earn National Attention Against Iowa State?

Top College Football Moneyline Bets for Week 5: Will Kansas Earn National Attention against Iowa State?

The top moneyline bets for the college football season are for Week 5. Kansas will earn national attention against Iowa State. Duke is getting enough respect for its turnaround. Nebraska is favored over anybody at this point.

Kansas is a +140 favorite at FanDuel. Duke is -125 at DraftKings. Indiana is +190 atFanDex.

Kansas is a top-15 team with a star quarterback, Josh Daniels. Iowa State's defense is not going to be able to stop Daniels this week. The Cyclones were beaten by Blake Shapen at Baylor last week, but they are still ranked 16th in the FBS. Iowa is better at winning with ball control than with possession.

Duke is 2-0 at home and has a balanced offense and a capable defense. Virginia is 0-3 against FBS opponents this year, including 0.2 on the road. The Cavaliers have the 123rd-ranked scoring offense (13 PPG)

Nebraska is a home favorite against Indiana. The Hoosiers are a moderate concern on defense. Nebraska has the worst defense in the Big Ten. Nebraska is 0-2 ATS as a favorite as the home team. Indiana's only win of the season was against South Dakota.

Kansas and Iowa State are playing in the college football game in Week 5.

College football moneyline picks made 9/27/2022 at 1:22 a.m. ET.