Week 8 NFL picks, odds, 2023 best bets from advanced model: This 5-way football parlay would pay out 25-1

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Week 8 NFL picks, odds, 2023 best bets from advanced model: This 5-way football parlay would pay out 25-1

After starting the season 5-0, the San Francisco 49ers have lost two straight games following a 22-17 setback on the road against the Minnesota Vikings. The 49ers will try to get back in the win column when Joe Burrow and the Cincinnati Bengals visit Levi's Stadium on Sunday. According to the latest Week 8 NFL odds, San Francisco is a 5.5-point favorite at home. The 49ers have covered the spread in their last 10 games at home and are 4-1 against the number in their last five meetings with the Bengals, making this matchup a game many bettors will target when locking in their Week 8 NFL bets. Before you make any Week 8 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 8 of the 2023 NFL season on an incredible 173-122 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 27-14 roll on top-rated NFL picks since Week 7 of last season.  

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 8. If you successfully parlay its picks, you'd be looking at a massive payout of around 25-1. You can only see the model's Week 8 NFL picks at SportsLine.

Top Week 8 NFL picks

After simulating every game 10,000 times, the model is high on the Kansas City Chiefs (-7) to cover on the road against the Denver Broncos. Chiefs tight end Travis Kelce is Patrick Mahomes' favorite target and has been on fire in recent weeks. Kelce has recorded at least nine receptions in his last three games and racked up 124 receiving yards in Kansas City's 19-8 victory over the Broncos on Oct. 12.

Kelce has scored a touchdown in two of his three road games this season and will remain a focal point for the Chiefs' offense in Denver. Kansas City's offense is averaging 285.4 passing yards per game, which ranks second in the league. Denver's defense is giving up 257.4 passing yards per game, the third-worst mark in the NFL. SportsLine's model is projecting Mahomes to throw for 300 yards, while Kelce finishes with 81 receiving yards, helping the Chiefs cover the spread in nearly 70% of simulations. See which other NFL parlay picks to make here.

How to make Week 8 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including backing several favorites that win with plenty of points to spare. You can only see the model's NFL Week 8 best bets and parlay at SportsLine

What are the model's top Week 8 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 8 NFL best bets from a model on a 173-122 run on top-rated picks, and find out.