Cubs vs. Reds odds, prediction, line: 2022 MLB picks, Thursday, May 26 best bets from proven baseball model

Cincinnati Reds take on Chicago Cubs on Thursday at 12:35 p.m. ET. The Reds won the first two games of the series. Chicago is a money-line favorite. SportsLine's advanced computer model simulates every MLB game 10,000 times. It's on a 41-30 roll on top-rated MLB money line picks through seven weeks.

Cubs vs. Reds is on Thursday, May 26. The money line is Cubs -115, the over-under is 8.5 runs and the run line -1. 5. Chicago Cubs are 11-10 in road games and 6-11 in home games.

Cubs are 11-10 in road games and 6-11 in home games.

Cubs are going to play Cincinnati on Thursday. Cubs left-hander Justin Steele is projected to start. The Cubs have a good bullpen with a 3.22 ERA. Cincinnati's offense is quite pedestrian. The Reds also have below-average walk rate of 8.1 percent.

Cubs and Reds are playing on Thursday. Hunter Greene has a 1.93 ERA in his last three starts. The Reds have a good chance to win because of Greene's performance. Chicago's starting pitcher has had a career 6.00 ERA against Cincinnati.

SportsLine's model is leaning over on the total and projects 9.5 combined runs. One side of the money line has all the value.