Lions vs. Packers odds, spread, line: Sunday Night Football picks, predictions from advanced NFL model

Green Bay Packers host Detroit Lions on Sunday Night Football at 8:20 p.m. ET. The stakes are high as the game is the final regular-season game of the 2022 NFL season. Green Bay is a 4.5-point favorite and the over/under for total points scored is 49. Detroit is coming off a 41-10 home win over the Chicago Bears, while Greenbay defeated the Minnesota Vikings 41.17 in Green.

Lions are 12-2 against the spread in their last 14 games against NFC North opponents. GB has covered the spreads in the past six games in this rivalry.

Lions are 12-2 against the spread in their last 14 games against NFC North opponents. GB has covered the spreads in the last six games in this rivalry.

The Packers are on a winning streak. They lost the first five games of the season, but have since won seven of their last 10. Christian Watson and Aaron Jones are the main threats in the passing game. The defense has been solid, allowing less than 20 points only once.

The Lions are ranked last overall by giving up nearly 399 yards per game. The Lions have made some improvements on the defensive side of the ball down the stretch. They will be motivated after their win over the Bears. Jared Goff is the quarterback for the fourth-ranked offense.

SportsLine's model is leaning over on the total and projects 50 combined points for Lions vs. Packers. One side of the spread hits nearly 60% of time.