Oregon State at Oregon line, prediction, odds: Ducks favored to clinch Pac-12 title game berth

The final chapter in the Pac-12 of the Oregon-Oregon State rivalry is upon us as the Ducks near their departure to the Big Ten. The Beavers will attempt to leave Oregon with a parting gift by potentially spoiling the Ducks’ postseason plans. However, the Ducks are favored by more than two touchdowns.

Oregon-Oregon State always has meaning, but no recent game has had the implications this one does. Oregon could kiss its College Football Playoff hopes goodbye with a loss, and could also miss out on the Pac-12 title game if Arizona beats Arizona State. Oregon State, No. 16 in the latest CFP rankings, still has a shot at a New Year’s Six bowl with a win.

Oregon hasn’t lost at home all year, but this is a rivalry game — anything can happen. The Beavers won last and have won two of the last three matchups, but the Ducks own seven straight home wins against Oregon State.

Can Oregon State slow another Heisman-hopeful quarterback in Bo Nix as it did last week against Washington’s Michael Penix Jr.? The Beavers held the Huskies scoreless in the second half, but still lost 22-20 in rainy conditions. Or will Nix ignite Oregon’s offense yet again and put another bullet point on his Heisman resume?

Oregon is 9-2 against the spread this season.

What is the spread for Oregon State at Oregon?

Expert picks against the spread

How to watch and stream Oregon State at Oregon

Kickoff is set for 8:30 p.m. ET on Friday at Autzen Stadium in Eugene. The game will be televised on FOX and streamed on the Fox Sports app.