Rams vs. Arizona Cardinals: Betting odds, lines, picks and predictions

Rams are 3½- or 4-point favorites against Arizona Cardinals. Rams and Cardinals are both 1-1. It's the first of six games against NFC West opponents.

Arizona Cardinals beat the Raiders last week. Los Angeles Rams lost to the Falcons. Rams committed three more turnovers and had a special teams mishap. Cardinals have one of the worst secondaries in the NFL. They have only one sack and zero interceptions. Rams have to start minimizing the mistakes. Arizona Cardinals are the most prolific scoring team in NFL and the least efficient. The Cardinals rank in bottom five in yards per play allowed.