Broncos vs. Seahawks odds, spread, line: Monday Night Football picks, predictions by NFL model that's 138-97

The Seattle Seahawks and Denver Broncos meet on Monday Night Football at 8:15 p.m. ET. Seattle is looking to improve after a 7-10 season last year, while Denver is trying to build on a last season's 7.10 record under first-time head coach Nathaniel Hackett. Caesars Sportsbook lists Denver as a 6.5-point road favorite, and the over/under is 44 in the latest Broncos vs. Seahawks odds. SportsLine's proven model simulates every NFL game 10,000 times and is up over $7,500 for $100 players on top-rated NFL picks since its inception.

SportsLine's computer model has made its Monday Night Football picks and predictions for Broncos vs. Seahawks. The model is very confident in its picks.

Broncos vs. Seahawks money line is Broncos -320, Seahawks +250. The game is expected to be won by the Broncos.

Denver has a lot of potential strengths and Seattle has some issues. Denver averaged 4.5 yards per carry on offense last season. Seattle finished No. 23 in the NFL in passing yards last year despite contributions from Russell Wilson. On defense, Seattle was No 28 in total defense and allowed 23. 5 first downs per game.

Geno Smith is the new quarterback for the Seattle Seahawks. Seattle finished No. 3 in the NFL with 5.0 yards per carry last season and scored 18 rushing touchdowns. Rashaad Penny rushed for more yards (671) than any player in NFL over the last five weeks of the 2021 season. Tyler Lockett has a streak of three straight 1,000-yard seasons and has caught at least eight touchdowns in four consecutive campaigns.

SportsLine's model is leaning Under on the total. It projects 41 combined points scored. One side of the spread hits in well over 50% of simulations.