Titans vs. Colts NFL Player Props, Odds

Anthony Richardson and the Indianapolis Colts host Derrick Henry and the Tennessee Titans as we make our best Titans vs. Colts NFL player props for Week 5 based on the best NFL odds

The Tennessee Titans lost 27-3 to the Cleveland Browns two weeks ago. Last week, after allowing the first three quarterbacks they faced to throw for 289 or more, they held Joe Burrow to 165 yards in their 27-3 win.

The Indianapolis Colts have played consecutive overtime games. Anthony Richardson has thrown for 200 or more yards in both of his complete games and has rushed for four touchdowns.

Here are our best Titans vs. Colts NFL player props for Week 5 (NFL odds via our best NFL betting sites; pick confidence based on a 1-to-5-star scale).

Titans vs. Colts NFL player props: Week 5

Derrick Henry Over 75.5 rushing yards (-110 via bet365) ⭐⭐⭐⭐

Henry has owned the Colts throughout his career. He has rushed for over 100 yards in six of his last seven games against his AFC South rivals, and there’s no reason to doubt him in Week 5.

Henry’s season started slowly, but last week, he ran the ball 22 times for 122 yards. The Colts have the 11th-worst rush defense in the NFL and haven’t played a particularly good running team.

Last week, Kyren Williams ran for 103 yards against the Colts, and the week before, Lamar Jackson went for 101. Look for Henry as the third 100-yard rusher against this team this year.

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Anthony Richardson anytime touchdown (+135 via FanDuel) ⭐⭐⭐

BetMGM has the worst price for this prop, as it's offering -110 odds. DraftKings, Caesars, and bet365 offer a significantly better price, ranging from +115 to +121. But FanDuel’s price is the best by far.

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The price doesn’t make much sense. In three games, Richardson has scored four rushing touchdowns. He had two against the Houston Texans before exiting in the first half with a concussion. 

The Titans are phenomenal against the run. They’ve allowed just one rushing touchdown all season, and they’re allowing just 70.0 yards per game. But Richardson isn’t a running back, he’s a running quarterback. And when his team gets in the red zone, he’s the primary person they try to get in the end zone.

Michael Pittman Jr. Over 57.5 receiving yards (-110 via bet365) ⭐⭐⭐

Pittman had a terrible game against the Los Angeles Rams. He had just one catch for 15 yards and was only targeted five times. However, we won’t let one game overshadow everything else he’s done this season.

In his first three games, Pittman hauled in at least eight catches, was targeted at least 11 times, and managed 56 or more yards in every contest. He’s still the number one target in Indianapolis, and his current line is a steal, considering the defense he’s going against.

The Titans still have one of the worst pass defenses in football despite their solid performance last week against the Bengals. Richardson’s passing ability has been just as consistent as his running. In a good matchup, we like Pittman to bounce back in a huge way. 

Titans vs. Colts player props made Friday at 9:39 a.m. ET

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