Titans vs. Colts Picks, Predictions NFL Week 4: Will Shoddy Offensive Lines Lead to Low-Scoring Battle?

Tennessee Titans and Indianapolis Colts each won their first game in Week 3. The Titans are 1-2 and the Colts are 0-1. DraftKings still considers the Indianapolis as the favorite, but Jacksonville is getting +225 odds. Tennessee has won four of the previous five games.

DraftKings offers a -3 line for the Titans vs. Colts game. Tennessee has attracted 45% of tickets but 56% in cash. The largest wagers are backing the Under.

Titans vs. Colts is a game that is expected to be low-scoring.

Titans beat Las Vegas in Week 3. The Colts are 1-1-2. Kansas City is 0-3-0. Tennessee set the tone with touchdowns on the first three drives. Derrick Henry had 143 scrimmage yards and a touchdown. FanDuel offers a half-point incentive for winning the game.

Titans and Colts are playing in the NFL's Week 4. The Colts had a good third-down conversion rate against the Chiefs. Matt Ryan was sacked five more times in Week 3 and has now fumbled seven times. Tennessee's offensive line was able to open running lanes for Henry.

Ryan is coming off his first game with two-plus passing touchdowns since Week 9 of the 2021 season. Before that, Ryan had one or fewer passing touchdown in his previous 11 games. The Colts are under 2.5 touchdowns.

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Titans vs. Colts is a game on 9/29/2022 at 5:52 a.m. ET.