USCFootball.com staff picks against the spread for USC vs. Notre Dame

The USC football team is playing against the Notre Dame Fighting Irish at the Coliseum at 4:30 p.m. PT. The Trojans are favored by 5.5 points. Last week the staff picked USC to win by 3 points, but the spread has moved to 4 points this week.

USC is favored to beat Notre Dame. Ryan Abraham thinks the Trojans will score a lot of points.

Gerard Martinez picks against USC this week. He is picking against them because he picked against against Cal last week and he is afraid of them this time.

USC Football.com staff picks against the spread for USC vs. Notre Dame. Notre Notre has a tight end named Michael Mayer.

USC is playing for bowl eligibility and a good record. Caleb Williams is red-hot and he's looking to put a stamp on his Heisman resume. Notre Dame lost to Stanford.

Notre Dame is getting USC at a perfect time. The Trojans are coming off a draining win over UCLA and looking at the Pac-12 championship game on a short week after they play Notre Dame. Notre Notre ran the football 47 times for 263 yards and won the time of possession by six minutes against Clemson.

USC is favored by 5.5 points against the spread. The game is at the Coliseum. USC's playoff hopes are on the line.

Notre Dame is favored by 5.5 points over USC. The Trojans are coming off a thrilling win over UCLA. The Irish are still the same team as before Brian Kelly's departure.

USC has the No. 2 ranked total offense in college football and the 17th ranked defense. The Trojans have showed they are a force to be reckoned with offensively. Notre Dame has shown they find ways to score.

USC is coming off an emotional win over UCLA and clinched a Pac-12 Championship Game berth next week. Notre Dame has won eight of its last nine games and beat then-No. 4 Clemson by 21 points a few weeks ago.

Ryan, Shotgun, Chris, Trevor, RJ, Gerard, Ahmad, Jack, Austin and Trevor are 7-4 this season.