Week 2 NFL odds: Early week betting picks and predictions

Summarized by: Live Sports Direct
 
Week 2 NFL odds: Early week betting picks and predictions

The NFL season kicked off last week with the Colts and Texans tying and the Steelers upsetting the Bengals. Oddsmakers have already posted interesting lines for this week's games.

The Chiefs are opening up as bigger favorites against the Super Bowl-contending Chargers. The Chargers are loaded up and down their roster, with newcomer Khalil Mack sacking Derek Carr three times in his Los Angeles debut. J.C. Jackson is trending in a positive direction, according to head coach Brandon Staley.

Colts haven't won a season opener since 2013. They tied last weekend to the Houston Texans. The Jaguars' offense may improve this season, but Trevor Lawrence missed a number of throws and looked inaccurate at points throughout the game. Jacksonville defense also left much to be desired, allowing Carson Wentz to throw four touchdowns and Washington to score 14 unanswered points.

Vikings are 2.5-point favorites against Eagles. Eagles' Super Bowl odds plummeted from +2500 to +1400 after Dak Prescott's thumb injury.

Minnesota's defense allowed 35 points to Detroit Lions. D’Andre Swift averaged 9.8 yards per carry against Philadelphia. Dalvin Cook is primed to replicate a similar performance. Kirk Cousins and Justin Jefferson may be the best big-play combination in football.